For all Public Groups, the deadline to submit your final picks is five (5) minutes before the start of the first game of the week. For almost all weeks, this will be during the morning on Saturday, but it will change if there are Friday games.
In a Private Group, the commissioner can set the deadline to be 3:00 p.m. PT on Friday (in weeks with Friday games, this deadline will move up one day, so the deadline will be 3:00 p.m. PT the day before the first game), five minutes before the start of the first game of the week or five minutes before the start of each game.
The Associated Press point spreads used in Yahoo! Sports College Football Pick'em are updated each day, with Thursday's lines serving as the game's official spreads.